{"product_id":"proteintech-67531-1-ig","title":"Proteintech, 67531-1-Ig, GPT\/ALT1 Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe GPT\/ALT1 (67531-1-Ig) by Proteintech is a Monoclonal antibody targeting GPT\/ALT1 in WB, IF\/ICC, ELISA applications with reactivity to human, mouse, rat, pig samples\n67531-1-Ig targets GPT\/ALT1 in WB, IF\/ICC, ELISA applications and shows reactivity with human, mouse, rat, pig samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: human milk, pig heart tissue,  pig liver tissue,  rat liver tissue,  mouse liver tissue,  rabbit heart tissue\nPositive IF\/ICC detected in: HepG2 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nGPT, also known as ALT1 (glutamate-pyruvate transaminase 1), catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat, pig\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: CatNo: Ag10453 Product name: Recombinant human GPT protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 147-496 aa of BC018207 Sequence: IPADPNNVFLSTGASDAIVTVLKLLVAGEGHTRTGVLIPIPQYPLYSATLAELGAVQVDYYLDEERAWALDVAELHRALGQARDHCRPRALCVINPGNPTGQVQTRECIEAVIRFAFEERLFLLADEVYQDNVYAAGSQFHSFKKVLMEMGPPYAGQQELASFHSTSKGYMGECGFRGGYVEVVNMDAAVQQQMLKLMSVRLCPPVPGQALLDLVVSPPAPTDPSFAQFQAEKQAVLAELAAKAKLTEQVFNEAPGISCNPVQGAMYSFPRVQLPPRAVERAQELGLAPDMFFCLRLLEETGICVVPGSGFGQREGTYHFRMTILPPLEKLRLLLEKLSRFHAKFTLEYS Predict reactive species\nFull Name: glutamic-pyruvate transaminase (alanine aminotransferase)\nCalculated Molecular Weight: 496 aa, 55 kDa\nObserved Molecular Weight: 52 kDa\nGenBank Accession Number: BC018207\nGene Symbol: ALT1\nGene ID (NCBI): 2875\nRRID: AB_2882750\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: P24298\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888281342121,"sku":"67531-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-67531-1-ig","provider":"Iright","version":"1.0","type":"link"}