{"product_id":"proteintech-68893-3-ig","title":"Proteintech, 68893-3-Ig, CD103 Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe CD103 (68893-3-Ig) by Proteintech is a Monoclonal antibody targeting CD103 in IF\/ICC, FC, ELISA applications with reactivity to human samples\n68893-3-Ig targets CD103 in IF\/ICC, FC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IF\/ICC detected in: 5 µg\/mL PHA ( 3 days) treated human PBMCs\nPositive FC detected in: 5 µg\/mL PHA for 3 days human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:500-1:2000\nFlow Cytometry (FC): FC : 0.20 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIntegrin alpha-E (CD103) is a member of the integrin family, specifically the αEβ7 heterodimer. It plays a crucial role in the immune system, particularly in the interaction between leukocytes and epithelial cells. Integrin alpha-E (CD103) is a critical component of the immune system, particularly in the context of mucosal immunity. Its ability to bind to E-cadherin and regulate the production of IFN-I in cDCs during viral infections highlights its multifaceted role in immune regulation and disease prevention. (PMID: 33584680)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: CatNo: Ag27410 Product name: Recombinant human Integrin alpha-E protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 147-456 aa of BC113436 Sequence: LLDPDARVDTGDCYSNKEGGGEDDVNTARQRRALEKEEEEDKEEEEDEEEEEAGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGLLSKLRYNIISMEGTVGDALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAA Predict reactive species\nFull Name: integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)\nCalculated Molecular Weight: 1179 aa, 130 kDa\nGenBank Accession Number: BC113436\nGene Symbol: ITGAE\nGene ID (NCBI): 3682\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: P38570\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888105410729,"sku":"68893-3-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-68893-3-ig","provider":"Iright","version":"1.0","type":"link"}