{"product_id":"proteintech-69023-1-ig","title":"Proteintech, 69023-1-Ig, NeutraKine® IL-17F Monoclonal antibody","description":"Size: 25ug \/ 100ug\nThe NeutraKine® IL-17F (69023-1-Ig) by Proteintech is a Monoclonal antibody targeting NeutraKine® IL-17F in ELISA, Neutralization applications with reactivity to Human samples\n69023-1-Ig targets NeutraKine® IL-17F in ELISA, Neutralization applications and shows reactivity with Human samples.\n\u003cb\u003eBackground Information\u003c\/b\u003e\nThe interleukin 17 (IL-17) family of cytokines contains 6 structurally related cytokines,  IL-17A, IL-17B, IL-17C, IL-17D, IL-17E and IL-17F. IL-17 family plays crucial roles in host defense against microbial organisms and in the development of inflammatory diseases.  IL-17A is a pro-inflammatory cytokine that also has the capacity to promote angiogenesis and osteoclastogenesis. IL-17F shares the highest homology with IL-17A and signals via a receptor composed by the IL-17RA and IL-17RC subunits. IL-17A and IL-17F can form IL-17A\/A or IL-17F\/F homodimers, IL-17A\/F heterodimers are also formed. IL-17A and IL-17F, produced by the Th17 CD4(+) T cell lineage, have been linked to a variety of inflammatory and autoimmune conditions. IL-17F levels are elevated in sera and lesional psoriatic skin compared to non-lesional tissue. IL-17F also has been implicated in the development of neutrophilic airway inflammation.This antibody is used to neutralize the bioactivity of IL-17F.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: RecombinantProtein Predict reactive species\nFull Name: interleukin 17F\nGene Symbol: IL-17F\nGene ID (NCBI): 112744\nRRID: AB_2918843\nConjugate: Unconjugated\nForm: Lyophilized Powder\nPurification Method: Protein G purification\nUNIPROT ID: Q96PD4\nStorage Buffer: Sterile PBS, pH 7.4.\nEndotoxin: \u0026lt;0.1 EU\/μg\nReconstitution: This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg\/mL in sterile H2O before use.\nStability and Storage: Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888304574633,"sku":"69023-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-69023-1-ig","provider":"Iright","version":"1.0","type":"link"}