{"product_id":"proteintech-69033-1-ig","title":"Proteintech, 69033-1-Ig, NeutraKine®M-CSF Monoclonal antibody","description":"Size: 25ug \/ 100ug\nThe NeutraKine®M-CSF (69033-1-Ig) by Proteintech is a Monoclonal antibody targeting NeutraKine®M-CSF in ELISA, Neutralization applications with reactivity to Human samples\n69033-1-Ig targets NeutraKine®M-CSF in ELISA, Neutralization applications and shows reactivity with Human samples.\n\u003cb\u003eBackground Information\u003c\/b\u003e\nM-CSF plays an essential role in the regulation of survival, proliferation, and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes. M-CSF promotes the release of proinflammatory chemokines and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. On the cellular level, M-CSF promotes reorganization of the actin cytoskeleton, regulates the formation of membrane ruffles, cell adhesion, and cell migration, and plays a role in lipoprotein clearance.This antibody is used to neutralize the bioactivity of  M-CSF.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nAffinity: K D =8.48 x 10 -9 M K Off =4.75 x 10 -4 M K On =5.60 x 10 4 M\nImmunogen: RecombinantProtein Predict reactive species\nFull Name: colony stimulating factor 1 (macrophage)\nGene Symbol: M-CSF\nGene ID (NCBI): 1435\nRRID: AB_3085334\nConjugate: Unconjugated\nForm: Lyophilized Powder\nPurification Method: Protein G purification\nUNIPROT ID: P09603\nStorage Buffer: Sterile PBS, pH 7.4.\nEndotoxin: \u0026lt;0.1 EU\/μg\nReconstitution: This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg\/mL in sterile H2O before use.\nStability and Storage: Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888305131689,"sku":"69033-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-69033-1-ig","provider":"Iright","version":"1.0","type":"link"}