{"product_id":"proteintech-80127-1-rr","title":"Proteintech, 80127-1-RR, Phospho-STK11\/LKB1 (Thr189) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-STK11\/LKB1 (Thr189) (80127-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-STK11\/LKB1 (Thr189) in WB, IF\/ICC, FC (Intra), ELISA applications with reactivity to human, mouse samples\n80127-1-RR targets Phospho-STK11\/LKB1 (Thr189) in WB, IF\/ICC, FC (Intra), ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: PC-3 cells, HEK-293 cells,  NIH\/3T3 cells,  Calyculin A treated HEK-293 cells,  Calyculin A treated PC-3 cells,  Calyculin A treated NIH\/3T3 cells\nPositive IF\/ICC detected in: Calyculin A treated PC-3 cells\nPositive FC (Intra) detected in: Calyculin A treated PC-3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:10000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\nFlow Cytometry (FC) (INTRA): FC (INTRA) : 0.13 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSTK11(serine\/threonine-protein kinase 11) is also named as LKB1, PJS, and belongs to the protein kinase superfamily. It controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. The tumour suppressor protein LKB1 is a serine\/threonine kinase that has been causally linked to Peutz-Jeghers syndrome (PJS). Defects in STK11 are a cause of Peutz-Jeghers syndrome (PJS) and defects in STK11 have been associated with testicular germ cell tumor (TGCT) and some sporadic cancers, especially lung cancers.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nCited Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: serine\/threonine kinase 11\nCalculated Molecular Weight: 49 kDa\nObserved Molecular Weight: 50-55 kDa\nGenBank Accession Number: BC007981\nGene Symbol: LKB1\nGene ID (NCBI): 6794\nRRID: AB_2918867\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q15831\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888377450665,"sku":"80127-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-80127-1-rr","provider":"Iright","version":"1.0","type":"link"}