{"product_id":"proteintech-81398-1-rr","title":"Proteintech, 81398-1-RR, Phospho-MNK1 (Thr250\/255) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-MNK1 (Thr250\/255) (81398-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-MNK1 (Thr250\/255) in WB, ELISA applications with reactivity to Human samples\n81398-1-RR targets Phospho-MNK1 (Thr250\/255) in WB, ELISA applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HEK-293T cells, HEK-293 cells,  λ phosphatase treated HEK-293T cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nMNK1\/MKNK1 (MAPK Interacting Serine\/Threonine Kinase 1) is a Ser\/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. MNK1 regulates diverse biologic processes including translation, cell proliferation, and differentiation through phosphorylation of different substrates(PMID: 29045529). Through phosphorylation MNK1 regulates the function of eukaryotic translation initiation factor 4E (eIF4E), a key player in translational control, whose expression is mostly upregulated in cancer patients.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: MAP kinase interacting serine\/threonine kinase 1\nCalculated Molecular Weight: 51 kDa\nObserved Molecular Weight: 51 kDa\nGenBank Accession Number: BC002755\nGene Symbol: MNK1\nGene ID (NCBI): 8569\nRRID: AB_2935427\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q9BUB5\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888439087273,"sku":"81398-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-81398-1-rr","provider":"Iright","version":"1.0","type":"link"}