{"product_id":"proteintech-81802-2-rr","title":"Proteintech, 81802-2-RR, NESP55,GNAS Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe NESP55,GNAS (81802-2-RR) by Proteintech is a Recombinant antibody targeting NESP55,GNAS in WB, IF\/ICC, ELISA applications with reactivity to human, mouse, rat samples\n81802-2-RR targets NESP55,GNAS in WB, IF\/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: SH-SY5Y cells, Jurkat cells,  MCGF-7 cells,  mouse liver tissue,  rat liver tissue\nPositive IF\/ICC detected in: MCF-7 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nGuanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 (GNAS1) is the ubiquitously expressed heterotrimeric G protein that couples receptors to the effector enzyme adenylyl cyclase and is required for receptor-stimulated intracellular cAMP generation. Mutations of Gs(alpha) residues involved in the GTPase reaction that lead to constitutive activation are present in endocrine tumors, fibrous dysplasia of bone, and McCune-Albright syndrome. The near two bands represent two different isoforms. The expression profile\/molecular weight observed are consistent with what has been described in the literature (PMID : 3258290).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Ag0197 Product name: Recombinant human NESP55,GNAS protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 230-394 aa of BC002722 Sequence: ERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL Predict reactive species\nFull Name: GNAS complex locus\nCalculated Molecular Weight: 45 kDa\nObserved Molecular Weight: 46 kDa\nGenBank Accession Number: BC002722\nGene Symbol: GNAS\nGene ID (NCBI): 2778\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P63092\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888652669097,"sku":"81802-2-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-81802-2-rr","provider":"Iright","version":"1.0","type":"link"}