Proteintech, 83000-6-RR, UNC13A Recombinant monoclonal antibody

Size: 20ul / 100ul The UNC13A (83000-6-RR) by Proteintech is a Recombinant antibody targeting UNC13A in IF/ICC, IF-P, ELISA applications with reactivity to human, rat samples 83000-6-RR targets UNC13A in IF/ICC, IF-P, ELISA applications and shows reactivity with human, rat samples. Tested Applications Positive IF-P detected in: rat brain tissue Positive IF/ICC detected in: SH-SY5Y cells Recommended dilution Immunofluorescence (IF)-P: IF-P : 1:200-1:800 Immunofluorescence (IF)/ICC: IF/ICC : 1:125-1:500 Background Information UNC13A, also named KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in INS secretion. The antibody is specific to UNC13A. Specification Tested Reactivity: human, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: unc-13 homolog A (C. elegans) Calculated Molecular Weight: 193 kDa GenBank Accession Number: NM_001080421 Gene Symbol: UNC13A Gene ID (NCBI): 23025 RRID: AB_3670747 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: Q9UPW8 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.