Proteintech, 83213-1-RR, CD86 Recombinant monoclonal antibody

Size: 20ul / 100ul The CD86 (83213-1-RR) by Proteintech is a Recombinant antibody targeting CD86 in IF/ICC, ELISA applications with reactivity to Mouse samples 83213-1-RR targets CD86 in IF/ICC, ELISA applications and shows reactivity with Mouse samples. Tested Applications Positive IF/ICC detected in: RAW 264.7 cells Recommended dilution Immunofluorescence (IF)/ICC: IF/ICC : 1:125-1:500 Background Information CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Specification Tested Reactivity: Mouse Cited Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: CD86 antigen Calculated Molecular Weight: 35 kDa GenBank Accession Number: NM_019388 Gene Symbol: Cd86 Gene ID (NCBI): 12524 RRID: AB_3670897 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P42082-1 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.