{"product_id":"proteintech-83547-3-rr","title":"Proteintech, 83547-3-RR, IL-2 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe IL-2 (83547-3-RR) by Proteintech is a Recombinant antibody targeting IL-2 in WB, ELISA applications with reactivity to mouse samples\n83547-3-RR targets IL-2 in WB, ELISA applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: PMA, Ionomycin and Brefeldin A treated EL-4 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nInterleukin-2 (Il2) is a protein initially identified as a T cell growth factor. Il2 is mainly produced by activated CD4+CD25- (helper) T cells, and induces the proliferation of these and others cells like CD8+ T cells, B and NK cells. For this reason, it has been used to treat immune-deficiencies like HIV, and induce immune response against tumors. Nevertheless, it has been shown that Il2 also acts as the main growth factor of CD4+CD25+ Regulatory T cells. Interleukin 2 mediates its functions in the target cell through the interleukin 2 receptor (Il2R). Il2R is a multimeric functional protein consisting of three different chains: Il2Rα, Il2Rβ and γc.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Eg0762 Product name: Recombinant Mouse IL-2 protein (His Tag) Source: mammalian cells -derived, pCMV (S9) Tag: N-6*His Domain: 21-169 aa of NM_008366 Sequence: APTSSSTSSSTAEAQQQQQQQQQQQQHLEQLLMDLQELLSRMENYRNLKLPRMLTFKFYLPKQATELKDLQCLEDELGPLRHVLDLTQSKSFQLEDAENFISNIRVTVVKLKGSDNTFECQFDDESATVVDFLRRWIAFCQSIISTSPQ Predict reactive species\nFull Name: interleukin 2\nCalculated Molecular Weight: 19 kDa\nObserved Molecular Weight: 15 kDa\nGenBank Accession Number: NM_008366\nGene Symbol: IL-2\nGene ID (NCBI): 16183\nRRID: AB_3671166\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P04351\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888644018345,"sku":"83547-3-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-83547-3-rr","provider":"Iright","version":"1.0","type":"link"}