{"product_id":"proteintech-83811-1-rr","title":"Proteintech, 83811-1-RR, Phospho-Histone H2B (Ser14) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-Histone H2B (Ser14) (83811-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-Histone H2B (Ser14) in WB, ELISA applications with reactivity to human, mouse samples\n83811-1-RR targets Phospho-Histone H2B (Ser14) in WB, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: PMA treated NIH\/3T3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nHistones are nuclear proteins that are classified into five major protein groups: histones H2A, H2B, H3, and H4 are known as the core histones. Post-translationally modified H2B proteins can modulate the nucleosome\/chromatin structure or DNA accessibility to affect the transcriptional pathways linked to embryonic development and cell differentiation. In addition, MST1 is known to phosphorylate histone H2B in vitro and has recently been shown to directly phosphorylate histone H2B at Ser14 in vivo. (PMID: 17548476)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: histone cluster 2, H2be\nCalculated Molecular Weight: 14 kDa\nObserved Molecular Weight: 14-17 kDa\nGenBank Accession Number: BC005827\nGene Symbol: Histone H2B\nGene ID (NCBI): 8349\nRRID: AB_3671399\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: Q16778\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888656011433,"sku":"83811-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-83811-1-rr","provider":"Iright","version":"1.0","type":"link"}