{"product_id":"proteintech-83833-5-rr","title":"Proteintech, 83833-5-RR, PTPRS Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe PTPRS (83833-5-RR) by Proteintech is a Recombinant antibody targeting PTPRS in WB, ELISA applications with reactivity to human samples\n83833-5-RR targets PTPRS in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A431 cells, SH-5Y5Y cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nProtein tyrosine phosphatase receptor type S (PTPRS, also known as R-PTP-S, PTPSIGMA, and R-PTP-sigma) is an integral membrane protein. It can promote oligomerization by binding to large heparan sulfate proteoglycan structures, and interact with NTRK1\/3, PPFIA1\/2\/3 (PMID: 25385546; 8524829; 9624153). The non-glycosylated molecular weight of PTPRS is 214 kDa, and the extracellular domain can be cleaved near the cell membrane by an endoprotease to generate a glycated 140 kDa protein. Variations and mutations of PTPRS are associated with Alzheimer's disease and cholangiocarcinoma (PMID: 38766183; 35991009).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Fusion Protein Predict reactive species\nFull Name: protein tyrosine phosphatase, receptor type, S\nCalculated Molecular Weight: 217 kDa\nObserved Molecular Weight: 140 kDa, 217 kDa\nGenBank Accession Number: NM_002850\nGene Symbol: PTPRS\nGene ID (NCBI): 5802\nRRID: AB_3671416\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: Q13332\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888812118185,"sku":"83833-5-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-83833-5-rr","provider":"Iright","version":"1.0","type":"link"}