{"product_id":"proteintech-84353-1-rr","title":"Proteintech, 84353-1-RR, SLCO2B1 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe SLCO2B1 (84353-1-RR) by Proteintech is a Recombinant antibody targeting SLCO2B1 in WB, ELISA applications with reactivity to human, mouse samples\n84353-1-RR targets SLCO2B1 in WB, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse liver tissue, mouse lung tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSolute carrier organic anion (SLCO) gene families encode organic anion transport proteins (OATP), which are membrane transporters widely expressed in the human body that influx numerous compounds and drugs including androgens. SLCO2B1 is a member of an organic anion transporter family and has previously been shown to transport a multitude of drugs and steroid hormone conjugates (PMID: 35714613). High expression of SLCO2B1 is known to associate with the resistance to androgen deprivation therapy in prostate cancer (PMID: 29581838). OATP2B1 was insensitive to endoglycosidase H, an enzyme that cleaves only high mannose glycans, as expected for a mature protein undergoing complex glycosylation.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: solute carrier organic anion transporter family, member 2B1\nCalculated Molecular Weight: 77 kDa\nObserved Molecular Weight: 61~74 kDa\nGenBank Accession Number: NM_007256\nGene Symbol: SLCO2B1\nGene ID (NCBI): 11309\nRRID: AB_3671891\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: O94956\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888823521449,"sku":"84353-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-84353-1-rr","provider":"Iright","version":"1.0","type":"link"}