{"product_id":"proteintech-84390-5-rr","title":"Proteintech, 84390-5-RR, IL-18R1\/CD218a Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe IL-18R1\/CD218a (84390-5-RR) by Proteintech is a Recombinant antibody targeting IL-18R1\/CD218a in WB, IF\/ICC, ELISA applications with reactivity to human samples\n84390-5-RR targets IL-18R1\/CD218a in WB, IF\/ICC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: NK-92 cells\nPositive IF\/ICC detected in: NK-92 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIL-18R1 (CD218a) is a component of the interleukin-18 receptor (IL-18R) complex, which is critical for the signaling of IL-18, a pro-inflammatory cytokine. This receptor complex, consisting of IL-18R1 and the IL-18 receptor accessory protein (IL-18RAP), belongs to the immunoglobulin-like family of interleukin-1 receptors (PMID: 35461924). IL-18R1 plays a significant role in inducing the production of interferon-gamma (IFN-γ) and other inflammatory cytokines, contributing to innate and adaptive immune responses (PMID: 2550053). It is also suggested to play a role in hypertension and chronic kidney disease, where the IL-18\/IL-18R1 signaling axis may have diagnostic and therapeutic potential (PMID: 35461924).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Recombinant Protein Predict reactive species\nFull Name: interleukin 18 receptor 1\nCalculated Molecular Weight: 541 aa, 62 kDa\nObserved Molecular Weight: 60-75 kDa\nGenBank Accession Number: BC093975\nGene Symbol: IL18R1\nGene ID (NCBI): 8809\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: Q13478\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888643821737,"sku":"84390-5-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-84390-5-rr","provider":"Iright","version":"1.0","type":"link"}