{"product_id":"proteintech-84468-4-rr","title":"Proteintech, 84468-4-RR, Integrin alpha-5\/CD49e Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Integrin alpha-5\/CD49e (84468-4-RR) by Proteintech is a Recombinant antibody targeting Integrin alpha-5\/CD49e in WB, IF\/ICC, ELISA applications with reactivity to human, mouse, pig samples\n84468-4-RR targets Integrin alpha-5\/CD49e in WB, IF\/ICC, ELISA applications and shows reactivity with human, mouse, pig samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A549 cells, HAP1 cells,  pig colon tissue,  HeLa cells,  NIH\/3T3 cells,  human placenta tissue\nPositive IF\/ICC detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:10000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIntegrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin alpha 5 (ITGA5), belongs to the integrin alpha chain family, primarily binds to Integrin beta 1 (ITGB1) to form an α5β1 heterodimer (PMID: 33711961). Integrin α5β1 is a specific receptor of fibronectin through its arginine-glycine-aspartic acid (RGD) binding site (PMID: 19608542). Integrin α5β1 plays roles in cell adhesion, migration and matrix formation, and has emerged as an essential mediator in many human carcinomas (PMID: 33408483).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, pig\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Recombinant Protein Predict reactive species\nFull Name: integrin, alpha 5 (fibronectin receptor, alpha polypeptide)\nCalculated Molecular Weight: 115 kDa\nObserved Molecular Weight: 140 kDa\nGenBank Accession Number: BC008786\nGene Symbol: Integrin alpha 5\nGene ID (NCBI): 3678\nRRID: AB_3671991\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P08648\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888373158057,"sku":"84468-4-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-84468-4-rr","provider":"Iright","version":"1.0","type":"link"}