{"product_id":"proteintech-84521-5-rr","title":"Proteintech, 84521-5-RR, ZC3H12A Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe ZC3H12A (84521-5-RR) by Proteintech is a Recombinant antibody targeting ZC3H12A in WB, IF\/ICC, FC (Intra), ELISA applications with reactivity to human samples\n84521-5-RR targets ZC3H12A in WB, IF\/ICC, FC (Intra), ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: K-562 cells, Raji cells,  HT-1376 cells,  MDA-MB-468 cells\nPositive IF\/ICC detected in: U-251 cells\nPositive FC (Intra) detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:125-1:500\nFlow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nZC3H12A, also named as MCPIP or MCPIP1, is a 599 amino acid protein, which contains one C3H1-type zinc finger and belongs to the ZC3H12 family. ZC3H12A localizes in the cytoplasm and nucleus. Increased expression of ZC3H12A is associated with ischemic heart disease. ZC3H12A has RNase activity and selectively degrades specific target mRNA species and modulates the immune response and inflammation by regulating the decay of specific mRNA molecules.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Ag13877 Product name: Recombinant human ZC3H12A protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 339-599 aa of BC005001 Sequence: ANALLSPPRAPSKDKNGRRPSPSSQSSSLLTESEQCSLDGKKLGAQASPGSRQEGLTQTYAPSGRSLAPSGGSGSSFGPTDWLPQTLDSLPYVSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPATAAFSAFGRAMGAGHFSVPADYPPAPPAFPPREYWSEPYPLPPPTSVLQEPPVQSPGAGRSPWGRADSLAKEQASVYTKLCGVFPPHLVEAVMGRFPQLLDPQQLAAEILSYKSQHPSE Predict reactive species\nFull Name: zinc finger CCCH-type containing 12A\nCalculated Molecular Weight: 599 aa, 66 kDa\nObserved Molecular Weight: 66 kDa\nGenBank Accession Number: BC005001\nGene Symbol: ZC3H12A\nGene ID (NCBI): 80149\nRRID: AB_3672028\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: Q5D1E8\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888843542697,"sku":"84521-5-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-84521-5-rr","provider":"Iright","version":"1.0","type":"link"}