{"product_id":"proteintech-84590-2-rr","title":"Proteintech, 84590-2-RR, Phospho-CRKL (Tyr207) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-CRKL (Tyr207) (84590-2-RR) by Proteintech is a Recombinant antibody targeting Phospho-CRKL (Tyr207) in WB, FC (Intra), ELISA applications with reactivity to human, mouse samples\n84590-2-RR targets Phospho-CRKL (Tyr207) in WB, FC (Intra), ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: NIH\/3T3 cells\nPositive FC (Intra) detected in: λ phosphatase treated NIH\/3T3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nFlow Cytometry (FC) (INTRA): FC (INTRA) : 0.13 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCrkL (v-crk avian sarcoma virus CT10 oncogene homolog-like) is a cytoplasmic adaptor protein that belongs to the Crk family of adaptors. Similar to other adaptor proteins, Crk functions primarily to assemble molecular complexes to distribute signals within the cell. The best studied regulatory mechanism of Crk proteins is the phosphorylation at a tyrosine located in a linker between the N- and C-terminal SH3 domains (Tyr221 in human CrkII, Tyr207 in human CrkL). (PMID: 24675776)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: v-crk sarcoma virus CT10 oncogene homolog (avian)-like\nCalculated Molecular Weight: 34 kDa\nObserved Molecular Weight: 39 kDa\nGenBank Accession Number: BC043500\nGene Symbol: CRKL\nGene ID (NCBI): 1399\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P46109\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888800420009,"sku":"84590-2-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-84590-2-rr","provider":"Iright","version":"1.0","type":"link"}