{"product_id":"proteintech-84727-5-rr","title":"Proteintech, 84727-5-RR, TMIGD2\/CD28H Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe TMIGD2\/CD28H (84727-5-RR) by Proteintech is a Recombinant antibody targeting TMIGD2\/CD28H in WB, ELISA applications with reactivity to human, pig samples\n84727-5-RR targets TMIGD2\/CD28H in WB, ELISA applications and shows reactivity with human, pig samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Jurkat cells, pig thymus tissue,  MOLT-4 cells,  HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nTransmembrane and immunoglobulin domain-containing protein 2 (TMIGD2, also known as CD28H and IGPR1), plays a role in cell-cell interaction, migration, and angiogenesis. Through interaction with HHLA2, it costimulates T-cells in the context of TCR-mediated activation and enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade (PMID: 22419821; 23784006). TMIGD2 has been associated with several diseases, particularly in the context of cancer. It is aberrantly expressed by human AML cells and can be used to identify and enrich functional LSCs (PMID: 38167704). The predicted molecular weight of the TMIGD2 protein is 31 kDa. The higher molecular weight of TMIGD2 could be associated with its potential glycosylation at its extracellular region (PMID: 22419821).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, pig\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Recombinant protein Predict reactive species\nFull Name: transmembrane and immunoglobulin domain containing 2\nCalculated Molecular Weight: 282 aa, 31 kDa\nObserved Molecular Weight: 48 kDa\nGenBank Accession Number: BC015655\nGene Symbol: TMIGD2\nGene ID (NCBI): 126259\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: Q96BF3\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888670232745,"sku":"84727-5-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-84727-5-rr","provider":"Iright","version":"1.0","type":"link"}