Proteintech, 84811-2-RR, TLR6 Recombinant monoclonal antibody

Size: 20ul / 100ul The TLR6 (84811-2-RR) by Proteintech is a Recombinant antibody targeting TLR6 in IF-P, ELISA applications with reactivity to human, mouse samples 84811-2-RR targets TLR6 in IF-P, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive IF-P detected in: mouse spleen tissue Recommended dilution Immunofluorescence (IF)-P: IF-P : 1:200-1:800 Background Information TLR6, also known as CD286, belongs to the Toll-like receptor (TLR) family which is important in the innate immune response to pathogens. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLR6 can form a heterodimer with TLR2. TLR6 and TLR2 are both recruited to the macrophage phagosome, where they recognize peptidoglycan, a Gram-positive pathogen component (PMID: 11095740). TLR6 interacts with CD36, following CD36 stimulation by oxLDL or amyloid-beta 42, and forms a heterodimer with TLR4. The trimeric complex is internalized and triggers an inflammatory response. Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: toll-like receptor 6 Calculated Molecular Weight: 480 aa, 56 kDa GenBank Accession Number: BC111755 Gene Symbol: TLR6 Gene ID (NCBI): 10333 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: Q9Y2C9 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.