{"product_id":"proteintech-84980-1-rr","title":"Proteintech, 84980-1-RR, Cyclin T1 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Cyclin T1 (84980-1-RR) by Proteintech is a Recombinant antibody targeting Cyclin T1 in WB, FC (Intra), ELISA, ChIP-qPCR applications with reactivity to human samples\n84980-1-RR targets Cyclin T1 in WB, FC (Intra), ELISA, ChIP-qPCR applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: K-562 cells, HeLa cells,  Jurkat cells,  HepG2 cells,  MCF-7 cells\nPositive FC (Intra) detected in: MCF-7 cells, U2OS cells\nPositive ChIP-qPCR detected in: HCT 116 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nFlow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension\nCHIP-QPCR: CHIP-QPCR : 1:10-1:100\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCCNT1, also named as Cyclin T1 and CycT1, belongs to the cyclin family and Cyclin C subfamily. It is a regulatory subunit of the cyclin-dependent kinase pair (CDK9\/cyclin-T1) complex which also called positive transcription elongation factor B (P-TEFb). In case of HIV or SIV infections, CCNT1 binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA). CCNT1 serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing transcription of viral genes. The antibody is specific to CCNT1.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: cyclin T1\nCalculated Molecular Weight: 81 kDa\nObserved Molecular Weight: 75-81 kDa\nGenBank Accession Number: NM_001240\nGene Symbol: Cyclin T1\nGene ID (NCBI): 904\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: O60563\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888732033193,"sku":"84980-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-84980-1-rr","provider":"Iright","version":"1.0","type":"link"}