{"product_id":"proteintech-85002-1-rr","title":"Proteintech, 85002-1-RR, Phospho-Cardiac Troponin I (Ser23\/24) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-Cardiac Troponin I (Ser23\/24) (85002-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-Cardiac Troponin I (Ser23\/24) in WB, ELISA applications with reactivity to human, mouse samples\n85002-1-RR targets Phospho-Cardiac Troponin I (Ser23\/24) in WB, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse heart tissue, λ phosphatase treated mouse heart tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCardiac Troponin I (cTnI) is produced by cardiac muscle. To date, most investigative effort in phosphorylation mediated regulation of cTnI function has focused on the actions of PKA and PKC. Evidence from studies in a variety of systems, ranging from reconstituted myofilament proteins to cultured myocytes or transgenic animals with heterologous expression of modified cTnI proteins, indicates that PKA-mediated functional effects (eg, decreased myofilament Ca2 sensitivity) are mediated principally through the phosphorylation of Ser22\/23 (equivalent to Ser23\/24, including the initiating Met, in the rodent sequence) within the unique N-terminal extension of cTnI. (PMID: 15514163)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: troponin I type 3 (cardiac)\nCalculated Molecular Weight: 210 aa, 24 kDa\nObserved Molecular Weight: 26 kDa\nGenBank Accession Number: BC096165\nGene Symbol: Cardiac Troponin I\nGene ID (NCBI): 7137\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: P19429\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888800026793,"sku":"85002-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-85002-1-rr","provider":"Iright","version":"1.0","type":"link"}