{"product_id":"proteintech-85021-4-rr","title":"Proteintech, 85021-4-RR, NKp46\/NCR1 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe NKp46\/NCR1 (85021-4-RR) by Proteintech is a Recombinant antibody targeting NKp46\/NCR1 in IF\/ICC, ELISA applications with reactivity to human samples\n85021-4-RR targets NKp46\/NCR1 in IF\/ICC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IF\/ICC detected in: NK-92 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nNKp46, also known as natural cytotoxicity triggering receptor 1 (NCR1), is a type I transmembrane protein belonging to the immunoglobulin superfamily. NKp46 is a key activating receptor expressed on natural killer (NK) cells. It plays a key role in the innate immune response by recognizing and binding to viral hemagglutinins and other ligands on infected or tumor cells. NKp46 mediates cytotoxicity and cytokine production upon engagement with its ligands, contributing to the elimination of infected or malignant cells.  Its expression and function are tightly regulated, and dysregulation of NKp46 has been implicated in various diseases, including viral infections, cancer, and autoimmune disorders. (PMID: 11234016; 29329948; 9730896; 9314561).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Recombinant protein Predict reactive species\nFull Name: natural cytotoxicity triggering receptor 1\nCalculated Molecular Weight: 34kDa\nGenBank Accession Number: \/\nGene Symbol: NCR1\nGene ID (NCBI): 9437\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: O76036-1\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888790524073,"sku":"85021-4-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-85021-4-rr","provider":"Iright","version":"1.0","type":"link"}