{"product_id":"proteintech-85066-5-rr","title":"Proteintech, 85066-5-RR, CD27 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe CD27 (85066-5-RR) by Proteintech is a Recombinant antibody targeting CD27 in WB, IF\/ICC, IF-P, ELISA applications with reactivity to human samples\n85066-5-RR targets CD27 in WB, IF\/ICC, IF-P, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Ramos cells\nPositive IF-P detected in: human tonsillitis tissue\nPositive IF\/ICC detected in: Ramos cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:10000\nImmunofluorescence (IF)-P: IF-P : 1:300-1:1200\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells, and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity (PMID: 11062504). It is a receptor for CD70 (CD27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways, as well as the JNK pathway (PMID: 19426224). CD27 may also play a role in apoptosis through association with SIVA1.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Recombinant protein Predict reactive species\nFull Name: CD27 molecule\nCalculated Molecular Weight: 29 kDa\nObserved Molecular Weight: 50 kDa\nGenBank Accession Number: BC012160\nGene Symbol: CD27\nGene ID (NCBI): 939\nENSEMBL Gene ID: ENSG00000139193\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P26842\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888720105641,"sku":"85066-5-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-85066-5-rr","provider":"Iright","version":"1.0","type":"link"}