{"product_id":"proteintech-85126-4-rr","title":"Proteintech, 85126-4-RR, PON2 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe PON2 (85126-4-RR) by Proteintech is a Recombinant antibody targeting PON2 in WB, ELISA applications with reactivity to mouse, rat samples\n85126-4-RR targets PON2 in WB, ELISA applications and shows reactivity with mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse heart tissue, L-929 cells,  RAW 264.7 cells,  mouse lung tissue,  rat lung tissue,  rat heart tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:10000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPON2 (Serum paraoxonase\/arylesterase 2) has antioxidant activity and can prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis. Highest levels of PON2 protein are found in the mouse lung and small intestine, followed by the heart and liver, while lower levels are present in the testis, kidney and brain. PON2 expression in tissues from female mice is always significantly higher than in male animals. There are also some reports showing two bands of 43 kDa and 53 kDa to be detected through western blot as the two isoforms of this protein. (PMID:21354197).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Eg2741 Product name: Recombinant Mouse Pon2 protein (rFc Tag) Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 30-354 aa of NM_183308.2 Sequence: ASREVESVDLPNCHLIKGIETGAEDIDILPNGLAFFSVGLKFPGLHSFAPDKPGGILMMDLKDERPRALELRVSWGFDLASFNPHGISTFIDDDDTVYLFVVNHPQFKSTVEIFKFQEEENSLLHLKTIKHELLPSVNDIIAVGPTHFYATNDHYFSDPFLKYLETYLNLHWANVVYYSPEEVKLVAEGFDSANGINISPDKKYVYVADILAHEIHVLEKQPNMNLTQLKVLQLGTLVDNLSIDPSSGDIWVGCHPNGQRLFVYHPNHPPASEVLRIQNILSEKPSVTTVYINNGSVLQGSSVATIYDRKLLVGTLYQKALYCEL Predict reactive species\nFull Name: paraoxonase 2\nCalculated Molecular Weight: 40 kDa\nObserved Molecular Weight: 39 kDa\nGenBank Accession Number: NM_183308.2\nGene Symbol: Pon2\nGene ID (NCBI): 330260\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q62086\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888809300137,"sku":"85126-4-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-85126-4-rr","provider":"Iright","version":"1.0","type":"link"}