{"product_id":"proteintech-85205-1-rr","title":"Proteintech, 85205-1-RR, CCKAR-specific Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe CCKAR-specific (85205-1-RR) by Proteintech is a Recombinant antibody targeting CCKAR-specific in WB, IP, ELISA applications with reactivity to human, mouse, rat samples\n85205-1-RR targets CCKAR-specific in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: SGC-7901 cells, mouse stomach tissue,  rat stomach tissue,  mouse pancreas tissue,  rat pancreas tissue,  mouse bladder tissue,  mouse lung tissue\nPositive IP detected in: mouse lung tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCholecystokinin (CCK) receptor, including CCKAR and CCKBR, is a receptor for cholecystokinin, mainly regulating pancreatic growth and enzyme secretion, and smooth muscle contraction of the gallbladder and stomach (PMID: 34556863). CCKAR (Cholecystokinin receptor type A) is primarily expressed in the alimentary tract, while CCKBR is mainly found in the brain and the stomach (PMID: 16816139). CCKAR is a biomarker for prognosis and asynchronous brain metastasis of non-small cell lung cancer (PMID: 36733361). The calculated MW of CCKAR is 48 kDa, but the observed MW is around 75 kDa, which may be with glycosylation modification.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: cholecystokinin A receptor\nCalculated Molecular Weight: 48 kDa\nObserved Molecular Weight: 75 kDa\nGenBank Accession Number: NM_000730\nGene Symbol: CCKAR\nGene ID (NCBI): 886\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P32238\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888599453865,"sku":"85205-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-85205-1-rr","provider":"Iright","version":"1.0","type":"link"}