{"product_id":"proteintech-85217-4-rr","title":"Proteintech, 85217-4-RR, Plakophilin 1 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Plakophilin 1 (85217-4-RR) by Proteintech is a Recombinant antibody targeting Plakophilin 1 in WB, ELISA applications with reactivity to human, mouse samples\n85217-4-RR targets Plakophilin 1 in WB, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse skin tissue, HEK-293 cells,  A431 cells,  PC-3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPlakophilin 1, also known as PKP1, B6P, is a member of the arm-repeat protein family. PKP1 contains arm-repeat (armadillo) domains, localizes to nuclei and cell desmosomes, and participates in linking cadherins to intermediate filaments in the cytoskeleton (PMID: 10747098). PKP1 contributes to epidermal morphogenesis and facilitates the formation of intermediate filaments. Mutations in PKP1 have been associated with the ectodermal dysplasia\/skin fragility syndrome (PubMed:9326952, 10852826).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Ag18153 Product name: Recombinant human PKP1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 412-726 aa of BC114571 Sequence: NLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLRNFTSRF Predict reactive species\nFull Name: plakophilin 1 (ectodermal dysplasia\/skin fragility syndrome)\nCalculated Molecular Weight: 747 aa, 83 kDa\nObserved Molecular Weight: 70-75 kDa\nGenBank Accession Number: BC114571\nGene Symbol: PKP1\nGene ID (NCBI): 5317\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q13835\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888806645929,"sku":"85217-4-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-85217-4-rr","provider":"Iright","version":"1.0","type":"link"}