{"product_id":"proteintech-85325-2-rr","title":"Proteintech, 85325-2-RR, RUNX1\/AML1 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe RUNX1\/AML1 (85325-2-RR) by Proteintech is a Recombinant antibody targeting RUNX1\/AML1 in WB, ELISA applications with reactivity to human, mouse, rat samples\n85325-2-RR targets RUNX1\/AML1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: PMA treated THP-1 cells, THP-1 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nRunt-related transcription factor 1 (RUNX1), also named AML1 or CBF alpha 2, is a 453 amino acid protein which contains one Runt domain. RUNX1 localizes in the nucleus and is expressed in all tissues except the brain and heart. RUNX1 is involved in hematopoiesis and is frequently targeted in human leukemia by chromosomal translocations that fuse the DNA-binding domain of RUNX1 to other transcription factors and corepressor molecules. In addition to its role in leukemogenesis, RUNX1 is also involved in the diversification of sensory neurons. RUNX1 exists in some isoforms with a range of MW 20-52 kDa. The calculated molecular weight of isoform 1 is 49 kDa; however, the modified protein ranges from approximately 49 to 55 kDa.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: runt-related transcription factor 1\nCalculated Molecular Weight: 51 kDa\nObserved Molecular Weight: 55 kDa\nGenBank Accession Number: NM_001754\nGene Symbol: RUNX1\nGene ID (NCBI): 861\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q01196\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888817819817,"sku":"85325-2-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-85325-2-rr","provider":"Iright","version":"1.0","type":"link"}