{"product_id":"proteintech-85768-2-rr","title":"Proteintech, 85768-2-RR, INVS Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe INVS (85768-2-RR) by Proteintech is a Recombinant antibody targeting INVS in WB, IP, ELISA applications with reactivity to human samples\n85768-2-RR targets INVS in WB, IP, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Jurkat cells, SH-SY5Y cells,  K-562 cells\nPositive IP detected in: K-562 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\n\u003cb\u003eBackground Information\u003c\/b\u003e\nINVS, short for inversin, plays a role in primary cilia function and involvement in the cell cycle. It is required for normal renal development and establishment of the left-right axis. INVS may be involved in Wnt signaling pathways by acting as a molecular switch between different them. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Ag0934 Product name: Recombinant human INVS protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-101 aa of BC006370 Sequence: MNKSENLLFAGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKALRTISTGRI Predict reactive species\nFull Name: inversin\nCalculated Molecular Weight: 118 kDa, 100 kDa\nObserved Molecular Weight: 100 kDa\nGenBank Accession Number: BC006370\nGene Symbol: INVS\nGene ID (NCBI): 27130\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q9Y283\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888771780777,"sku":"85768-2-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-85768-2-rr","provider":"Iright","version":"1.0","type":"link"}