Product Description
Size: 20ul / 100ul
The SYNJ2BP (85870-4-RR) by Proteintech is a Recombinant antibody targeting SYNJ2BP in WB, IF/ICC, ELISA applications with reactivity to human, rat samples
85870-4-RR targets SYNJ2BP in WB, IF/ICC, ELISA applications and shows reactivity with human, rat samples.
Tested Applications
Positive WB detected in: A549 cells, rat kidney tissue, SGC-7901 cells, SH-SY5Y cells, human heart tissue
Positive IF/ICC detected in: HeLa cells
Recommended dilution
Western Blot (WB): WB : 1:2000-1:10000
Immunofluorescence (IF)/ICC: IF/ICC : 1:250-1:1000
Background Information
Activin, a member of the TGF-beta superfamily, plays important roles in reproductive tissues as a stimulator of follicle-stimulating hormone (FSH) secretion and inhibits the proliferation of breast cancer cells. Activin receptor-interacting protein 2 (ARIP2), also known as synaptojanin-2-binding protein (SYNJ2BP), is located in the outer membrane of mitochondria. SYNJ2BP is widely distributed in various human tissues, and has been recently identified in mouse tissues as a regulatory protein of activin signal transduction by interacting with activin type II receptors. SYNJ2BP may be a putative growth-promoting factor involved in breast tumorigenesis and tumor development. A double band of size 15.9 kDa can be detected in Western blot (PMID: 23284606).
Specification
Tested Reactivity: human, rat
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Ag8130 Product name: Recombinant human ARIP2; SYNJ2BP protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-112 aa of BC007704 Sequence: MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQVQNGPIGHRGE Predict reactive species
Full Name: synaptojanin 2 binding protein
Calculated Molecular Weight: 145 aa, 16 kDa
Observed Molecular Weight: 16 kDa
GenBank Accession Number: BC007704
Gene Symbol: SYNJ2BP
Gene ID (NCBI): 55333
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: P57105
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
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