{"product_id":"proteintech-86029-1-rr","title":"Proteintech, 86029-1-RR, Serpinc1 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Serpinc1 (86029-1-RR) by Proteintech is a Recombinant antibody targeting Serpinc1 in WB, IHC, ELISA applications with reactivity to mouse, rat samples\n86029-1-RR targets Serpinc1 in WB, IHC, ELISA applications and shows reactivity with mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse serum, rat serum,  mouse liver tissue\nPositive IHC detected in: mouse liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nImmunohistochemistry (IHC): IHC : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSERPINC1 is a gene encoding antithrombin, also known as antithrombin III. The main function of antithrombin is to inhibit coagulation proteases such as thrombin and factor Xa, thereby preventing excessive coagulation and maintaining normal hemostasis and blood flow. Mutations in the SERPINC1 gene can lead to antithrombin deficiency (ATD), which is an autosomal dominant genetic disorder. The expression profile\/molecular weight observed is consistent with what has been described in the literature (PMID: 3609301, PMID: 25485983, PMID: 35935621).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Eg2949 Product name: Recombinant Mouse Serpinc1 protein (rFc Tag) Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 33-465 aa of NM_080844.4 Sequence: HGNPVDDICIAKPRDIPVNPLCIYRSPGKKATEEDGSEQKVPEATNRRVWELSKANSRFATNFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLKQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSDLVSANRLFGDKSLTFNESYQDVSEVVYGAKLQPLDFKENPEQSRVTINNWVANKTEGRIKDVIPQGAINELTALVLVNTIYFKGLWKSKFSPENTRKEPFYKVDGQSCPVPMMYQEGKFKYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEQELTPELLQEWLDELSETMLVVHMPRFRTEDGFSLKEQLQDMGLIDLFSPEKSQLPGIVAGGRDDLYVSDAFHKAFLEVNEEGSEAAASTSVVITGRSLNPNRVTFKANRPFLVLIREVALNTIIFMGRVANPCVN Predict reactive species\nFull Name: serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1\nCalculated Molecular Weight: 52 kDa\nObserved Molecular Weight: 52 kDa\nGenBank Accession Number: NM_080844.4\nGene Symbol: Serpinc1\nGene ID (NCBI): 11905\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P32261\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888666169513,"sku":"86029-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-86029-1-rr","provider":"Iright","version":"1.0","type":"link"}