Proteintech, 86200-3-RR, PSMD12 Recombinant monoclonal antibody

Size: 20ul / 100ul The PSMD12 (86200-3-RR) by Proteintech is a Recombinant antibody targeting PSMD12 in WB, ELISA applications with reactivity to human, mouse, rat samples 86200-3-RR targets PSMD12 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: HeLa cells, MCF-7 cells, HT-29 cells, HepG2 cells, mouse heart tissue, mouse lung tissue, rat lung tissue Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information Proteasome 26S subunit, non-ATPase 12 (PSMD12; also known as RPN5) was first discovered in fission yeast. It is a non-ATPase subunit of the 19S regulator of the 26S proteasome complex, which is involved in regulating the cell cycle, repairing DNA damage, and regulating apoptosis by mediating the internal protein balance through the removal of misfolded proteins or damaged intracellular substructures. In addition, PSMD12 contributes to tumor cell growth and apoptosis in breast cancer. (PMID: 33987398) Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag1957 Product name: Recombinant human PSMD12 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-320 aa of BC019062 Sequence: MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAKEGRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTL Predict reactive species Full Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 Calculated Molecular Weight: 456 aa, 53 kDa Observed Molecular Weight: 50-55 kDa GenBank Accession Number: BC019062 Gene Symbol: PSMD12 Gene ID (NCBI): 5718 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: O00232 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.