{"product_id":"proteintech-86486-1-rr","title":"Proteintech, 86486-1-RR, MYST2 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe MYST2 (86486-1-RR) by Proteintech is a Recombinant antibody targeting MYST2 in WB, ELISA applications with reactivity to human, mouse samples\n86486-1-RR targets MYST2 in WB, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: MCF-7 cells, HeLa cells,  Jurkat cells,  MOLT-4 cells,  NIH\/3T3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:10000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nMYST2, also named as HBO1, HBOa MOZ, YBF2\/SAS3, SAS2 and TIP60 protein 2, belongs to the MYST (SAS\/MOZ) family. It specifically represses AR mediated transcription. MYST2 is a candidate oncogene. It enhances the anchorage-independent growth of breast cancer cells.(PMID:19372580) MYST2 is a histone acetyltransferase (HAT) which could exert oncogenic function in breast cancer. It is an important downstream molecule of ERa, and ERK1\/2 signaling pathway may involved in the expression of HBO1 increased by E2.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Ag4693 Product name: Recombinant human MYST2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-370 aa of BC032640 Sequence: MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEF Predict reactive species\nFull Name: MYST histone acetyltransferase 2\nCalculated Molecular Weight: 611 aa, 71 kDa\nObserved Molecular Weight: 71-75 kDa\nGenBank Accession Number: BC032640\nGene Symbol: MYST2\nGene ID (NCBI): 11143\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: O95251\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888787869865,"sku":"86486-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-86486-1-rr","provider":"Iright","version":"1.0","type":"link"}