Proteintech, 86491-1-RR, PSMB6 Recombinant monoclonal antibody

Size: 20ul / 100ul The PSMB6 (86491-1-RR) by Proteintech is a Recombinant antibody targeting PSMB6 in WB, IF/ICC, ELISA applications with reactivity to human, mouse samples 86491-1-RR targets PSMB6 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: HeLa cells, DU 145 cells, PC-3 cells, K-562 cells, MCF-7 cells, Neuro-2a cells, C2C12 cells Positive IF/ICC detected in: HeLa cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Immunofluorescence (IF)/ICC: IF/ICC : 1:250-1:1000 Background Information PSMB6(Proteasome subunit beta type-6) is also named as LMPY, Y and belongs to the peptidase T1B family.The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.It may also catalyzes basal processing of intracellular antigens.It can be up-regulated in anaplastic thyroid cancer cell lines and down-regulated by IFNG/IFN-gamma (at protein level)(PMID:8066462;15613457). Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag2296 Product name: Recombinant human PSMB6 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-239 aa of BC000835 Sequence: MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPPA Predict reactive species Full Name: proteasome (prosome, macropain) subunit, beta type, 6 Calculated Molecular Weight: 239 aa, 25 kDa Observed Molecular Weight: 25 kDa GenBank Accession Number: BC000835 Gene Symbol: PSMB6 Gene ID (NCBI): 5694 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P28072 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.