{"product_id":"proteintech-86531-2-rr","title":"Proteintech, 86531-2-RR, Cytokeratin 40 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Cytokeratin 40 (86531-2-RR) by Proteintech is a Recombinant antibody targeting Cytokeratin 40 in WB, ELISA applications with reactivity to human samples\n86531-2-RR targets Cytokeratin 40 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: 5637 cells, MCF-7 cells,  HaCaT cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nKeratin 40 (KRT40) is a type I (acidic) keratin protein encoded by the KRT40 gene located on human chromosome 17q21.2. As a member of the intermediate filament (IF) protein superfamily, keratin 40 contributes to the cytoskeletal framework of epithelial cells, forming heteropolymeric filaments that provide mechanical support and structural integrity to tissues such as hair follicles, wool fibers, and certain glandular epithelia. KRT40 is expressed at relatively low levels under normal physiological conditions, but its expression becomes significant in specialized contexts. In hair biology, KRT40 is considered a hub gene involved in hair follicle development, cell cycle regulation, and melanogenesis, with its transcripts localized specifically to the fiber cuticle in species like sheep and yak, indicating a structural role in hair shaft formation.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: keratin 40\nCalculated Molecular Weight: 431 aa, 48 kDa\nObserved Molecular Weight: 48 kDa\nGenBank Accession Number: BC150191\nGene Symbol: Cytokeratin 40\nGene ID (NCBI): 125115\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q6A162\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888733409449,"sku":"86531-2-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-86531-2-rr","provider":"Iright","version":"1.0","type":"link"}