{"product_id":"proteintech-86794-1-rr","title":"Proteintech, 86794-1-RR, Phospho-AMPK Beta 2 (Ser39) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-AMPK Beta 2 (Ser39) (86794-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-AMPK Beta 2 (Ser39) in WB, ELISA applications with reactivity to human, mouse, rat samples\n86794-1-RR targets Phospho-AMPK Beta 2 (Ser39) in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, A431 cells,  mouse skeletal muscle tissue,  rat skeletal muscle tissue,  λ phosphatase treated HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nAMPK beta 2 is a regulatory subunit of the AMP-activated protein kinase (AMPK), which is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits.  AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. AMPK beta 2 may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: protein kinase, AMP-activated, beta 2 non-catalytic subunit\nCalculated Molecular Weight: 30 kDa\nObserved Molecular Weight: 34 kDa\nGenBank Accession Number: BC053610\nGene Symbol: AMPK Beta 2\nGene ID (NCBI): 5565\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: O43741\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888799469737,"sku":"86794-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-86794-1-rr","provider":"Iright","version":"1.0","type":"link"}