Product Description
Size: 20ul / 100ul
The UPK1A (86799-1-RR) by Proteintech is a Recombinant antibody targeting UPK1A in WB, IF-P, ELISA applications with reactivity to human, mouse, rat samples
86799-1-RR targets UPK1A in WB, IF-P, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: mouse bladder tissue, rat bladder tissue
Positive IF-P detected in: mouse bladder tissue
Recommended dilution
Western Blot (WB): WB : 1:2000-1:10000
Immunofluorescence (IF)-P: IF-P : 1:50-1:500
Background Information
Uroplakins are a group of urothelial differentiation-related membrane proteins. They are components of the asymmetric unit membrane (AUM), which forms the apical plaques of mammalian urothelium and is believed to play a role in strengthening the urothelial apical surface thus preventing the cells from rupturing during bladder distention (PMID: 8175808). Uroplakin-1a (UPK1A) belongs to the tetraspanin (TM4SF) family. UPK1A plays an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane.
Specification
Tested Reactivity: human, mouse, rat
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Ag17356 Product name: Recombinant human UPK1A protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 111-230 aa of BC107098 Sequence: CITSYTHRDYMVSNPSLITKQMLTFYSADTDQGQELTRLWDRVMIEQECCGTSGPMDWVNFTSAFRAATPEVVFPWPPLCCRRTGNFIPLNEEGCRLGHMDYLFTKGCFEHIGHAIDSYT Predict reactive species
Full Name: uroplakin 1A
Calculated Molecular Weight: 258 aa, 29 kDa
Observed Molecular Weight: 29 kDa
GenBank Accession Number: BC107098
Gene Symbol: UPK1A
Gene ID (NCBI): 11045
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: O00322
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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