Proteintech, 87104-3-RR, VASP Recombinant monoclonal antibody

Size: 20ul / 100ul The VASP (87104-3-RR) by Proteintech is a Recombinant antibody targeting VASP in WB, ELISA applications with reactivity to human, mouse, rat samples 87104-3-RR targets VASP in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: HeLa cells, NIH/3T3 cells, C6 cells Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Background Information VASP belongs to the Ena/VASP family. Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. VASP plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation. Human platelet activation is inhibited by agents such as prostaglandins and NO donors, which elevate cAMP or cGMP levels. VASP is phosphorylated in human platelets in response to both cAMP- and cGMP-elevating agents, and its phosphorylation correlates with platelet inhibition. Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: vasodilator-stimulated phosphoprotein Calculated Molecular Weight: 380 aa, 40 kDa Observed Molecular Weight: ~ 50 kDa GenBank Accession Number: BC038224 Gene Symbol: VASP Gene ID (NCBI): 7408 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P50552 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.