Proteintech, 87340-1-RR, SLC39A6/ZIP6 Recombinant monoclonal antibody

Size: 20ul / 100ul The SLC39A6/ZIP6 (87340-1-RR) by Proteintech is a Recombinant antibody targeting SLC39A6/ZIP6 in WB, ELISA applications with reactivity to human, mouse samples 87340-1-RR targets SLC39A6/ZIP6 in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: HepG2 cells, HeLa cells, HEK-293T cells, Jurkat cells, HuH-7 cells, 4T1 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:8000 Background Information The zinc transporter LIV-1 (also known as SLC39A6 or ZIP6) was originally identified as an estrogen-induced gene in breast cancer cells. Elevated LIV-1 expression is reportedly related to cancer progression in various types of cancer, including breast, prostate, pancreatic, cervical and liver cancers. While correlation of LIV-1 and prognosis may vary. LIV 1 has 3 isoforms with MW of 85-100 (glycosylation and phosphorylation), 48 and 32 kDa while migrates as different bands in different lysates in SDS-PAGE. Furthermore, it has been reported in the papers that full-length SLC39A6/ZIP6, as the pro-protein, is predicted to be 85 kDa and produces a 103 kDa band, the N-terminal fragment after cleavage is 35 kDa, and the cleaved ZIP6 is 68 kDa (PMID: 23919497, PMID: 26444413). Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: solute carrier family 39 (zinc transporter), member 6 Calculated Molecular Weight: 85 kDa Observed Molecular Weight: 86-100 kDa GenBank Accession Number: BC039498 Gene Symbol: SLC39A6/ZIP6 Gene ID (NCBI): 25800 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q13433 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.