Proteintech, 87404-1-RR, VEGFA Recombinant monoclonal antibody

Size: 20ul / 100ul The VEGFA (87404-1-RR) by Proteintech is a Recombinant antibody targeting VEGFA in WB, ELISA applications with reactivity to human samples 87404-1-RR targets VEGFA in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HUVEC cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are associated with microvascular complications of diabetes type 1 (MVCD1). VEGFA has 17 isoforms with MW from 16 to 45 kDa. Some isoforms have homodimer forms (e.g.; VEGFA189 38 kDa or VEFGA110 34 kDa). VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids (PMID:15602010 ). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Product name: HumanKine® recombinant human VEGF121 protein Source: -derived, Tag: Domain: of Sequence: Predict reactive species Full Name: vascular endothelial growth factor A Observed Molecular Weight: 27 kDa Gene Symbol: VEGFA Gene ID (NCBI): 7422 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P15692 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.