{"product_id":"proteintech-87408-1-rr","title":"Proteintech, 87408-1-RR, Integrin alpha-8 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Integrin alpha-8 (87408-1-RR) by Proteintech is a Recombinant antibody targeting Integrin alpha-8 in WB, IF-P, ELISA applications with reactivity to human, mouse, rat samples\n87408-1-RR targets Integrin alpha-8 in WB, IF-P, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse spleen tissue, human kidney tissue,  mouse lung tissue,  mouse kidney tissue,  rat lung tissue,  rat spleen tissue,  rat kidney tissue\nPositive IF-P detected in: mouse lung tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nImmunofluorescence (IF)-P: IF-P : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIntegrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. Integrin alpha-8 is a single-pass type I membrane protein that forms a heterodimer with integrin beta-1 to serve as a receptor for RGD-containing matrix molecules (fibronectin, vitronectin, tenascin C, osteopontin, and nephronectin) (PMID: 33000355). Integrin alpha-8 beta-1 plays a critical role in epithelial-mesenchymal interactions and functions in the genesis of kidney and probably of other organs (PMID: 9054500; 19769957). The apparent molecular weight of integrin alpha-8 is larger than the calculated molecular weight of 117 kDa, possibly due to glycosylation (PMID: 7768999).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Eg10469 Product name: Recombinant mouse ITA8 protein Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-Twin-Strep-Tag Domain: 10011446 of Sequence: \\ Predict reactive species\nFull Name: integrin alpha 8\nCalculated Molecular Weight: 117 kDa\nObserved Molecular Weight: 140 kDa\nGene Symbol: Itga8\nGene ID (NCBI): 241226\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: A2ARA8\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888644772009,"sku":"87408-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-87408-1-rr","provider":"Iright","version":"1.0","type":"link"}