{"product_id":"proteintech-87416-2-rr","title":"Proteintech, 87416-2-RR, Integrin beta 4 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Integrin beta 4 (87416-2-RR) by Proteintech is a Recombinant antibody targeting Integrin beta 4 in WB, ELISA applications with reactivity to human, mouse, rat samples\n87416-2-RR targets Integrin beta 4 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: BxPC-3 cells, mouse skin tissue,  rat skin tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIntegrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin beta-4 is predominantly expressed in squamous epithelial cells, endothelial cells, immature thymocytes, Schwann cells, and fibroblasts of the peripheral nervous system (PMID: 28084395). Integrin beta-4 pairs with alpha-6, and the heterodimeric integrin alpha-6\/beta-4 is a receptor for laminin. Integrin alpha-6\/beta-4 plays a critical structural role in the hemidesmosome of epithelial cells, and also plays a role in the invasive and metastatic phenotype of various cancers.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Eg10479 Product name: Recombinant human ITB4 protein Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-Twin-Strep-Tag Domain: 10011436 of Sequence: \\ Predict reactive species\nFull Name: integrin, beta 4\nObserved Molecular Weight: 200 kDa\nGene Symbol: Integrin beta 4\nGene ID (NCBI): 3691\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888771256489,"sku":"87416-2-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-87416-2-rr","provider":"Iright","version":"1.0","type":"link"}