{"product_id":"proteintech-87534-1-rr","title":"Proteintech, 87534-1-RR, Phospho-RPS6KA3 (Ser227) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-RPS6KA3 (Ser227) (87534-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-RPS6KA3 (Ser227) in WB, ELISA applications with reactivity to human samples\n87534-1-RR targets Phospho-RPS6KA3 (Ser227) in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HepG2 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:10000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nRibosomal S6 Kinase 2 (RSK2), a member of the p90RSK family of serine\/threonine kinases, is known to be phosphorylated at Ser227 and Th577 in response to Adriamycin-induced DNA damage. This phosphorylation promotes RSK2 nuclear translocation and enhances RSK2 and Atm interactions in the nuclear fraction, playing an important role in the DNA damage pathway that maintains genomic stability by mediating cell cycle progression and DNA repair.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: ribosomal protein S6 kinase, 90kDa, polypeptide 3\nCalculated Molecular Weight: 740 aa, 84 kDa\nObserved Molecular Weight: 84 kDa\nGenBank Accession Number: BC096301\nGene Symbol: RSK2\nGene ID (NCBI): 6197\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P51812\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888804319401,"sku":"87534-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-87534-1-rr","provider":"Iright","version":"1.0","type":"link"}