Product Description
Size: 20ul / 100ul
The SSTR2 (87663-1-RR) by Proteintech is a Recombinant antibody targeting SSTR2 in WB, ELISA applications with reactivity to human, mouse samples
87663-1-RR targets SSTR2 in WB, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive WB detected in: SH-SY5Y cells, Neuro-2a cells, C6 cells, mouse brian tissue
Recommended dilution
Western Blot (WB): WB : 1:1000-1:6000
Background Information
Somatostatin receptor 2 (SSTR2) is a G-protein coupled membrane receptor expressed in a variety of neural and neurosecretory tissue types. In neuroendocrine tumors (NETs), in which Somatostatin receptors (SSTRs) are commonly expressed, the detection of SSTR2 expression has both diagnostic and therapeutic potential. Besides NETs, SSTR2 immunostaining can be detected in other types of tumor cells(PMID:34786053). Moreover, SSTR2 is consistently expressed in Olfactory neuroblastoma (ONB) suggesting a role for somatostatin-analog based imaging and therapy in this disease. More generally, SSTR2 may be another marker of neuroendocrine diferentiation in ONB(PMID:33929681).
Specification
Tested Reactivity: human, mouse
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Ag14205 Product name: Recombinant human SSTR2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-60 aa of BC019610 Sequence: MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG Predict reactive species
Full Name: somatostatin receptor 2
Calculated Molecular Weight: 369 aa, 41 kDa
Observed Molecular Weight: 85 kDa
GenBank Accession Number: BC019610
Gene Symbol: SSTR2
Gene ID (NCBI): 6752
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: P30874
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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