{"product_id":"proteintech-98058-1-rr","title":"Proteintech, 98058-1-RR, Anti-Mouse ICOSLG\/B7-H2\/CD275 Rabbit Recombinant Antibody","description":"Size: 100ug\nThe ICOSLG\/B7-H2\/CD275 (98058-1-RR) by Proteintech is a Recombinant antibody targeting ICOSLG\/B7-H2\/CD275 in FC applications with reactivity to mouse samples\n98058-1-RR targets ICOSLG\/B7-H2\/CD275 in FC applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: mouse splenocytes\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nICOSLG, also known as B7H2 or GL50, is a type I transmembrane glycoprotein belonging to the B7 ligand family. ICOSLG is extensively expressed on professional antigen-presenting cells including B cells, macrophages, and dendritic cells, as well as non-lymphoid cells including mesenchymal stem cells, endothelial cells, fibroblasts, and tumor cells (PMID: 33756276; 35800767). It is a specific ligand for the T-cell-specific cell surface receptor ICOS and acts as a co-stimulatory molecule (PMID: 11023515; 11007762). The interaction of ICOSLG and ICOS plays important roles in the activation, proliferation, differentiation, and cytokine production of T cells as well as in the antibody secretion from B cells during secondary immune responses (PMID: 21851236).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Recombinant protein Predict reactive species\nFull Name: icos ligand\nCalculated Molecular Weight: 36 kDa\nGenBank Accession Number: NM_015790.3\nGene Symbol: CD275\nGene ID (NCBI): 50723\nRRID: AB_3672205\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: Q9JHJ8-1\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2 - 8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888571142313,"sku":"98058-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-98058-1-rr","provider":"Iright","version":"1.0","type":"link"}