{"product_id":"proteintech-98171-1-rr","title":"Proteintech, 98171-1-RR, Anti-Human Integrin alpha-5\/CD49e Rabbit Recombinant Antibody","description":"Size: 100ug\nThe Integrin alpha-5\/CD49e (98171-1-RR) by Proteintech is a Recombinant antibody targeting Integrin alpha-5\/CD49e in FC applications with reactivity to human samples\n98171-1-RR targets Integrin alpha-5\/CD49e in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIntegrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin alpha-5 (ITGA5, also known as CD49e), belongs to the integrin alpha chain family, primarily binds to Integrin beta 1 (ITGB1) to form an α5β1 heterodimer (PMID: 33711961). Integrin α5β1 is a specific receptor of fibronectin through its arginine-glycine-aspartic acid (RGD) binding site (PMID: 19608542). Integrin α5β1 plays roles in cell adhesion, migration and matrix formation, and has emerged as an essential mediator in many human carcinomas (PMID: 33408483).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Recombinant Protein Predict reactive species\nFull Name: integrin, alpha 5 (fibronectin receptor, alpha polypeptide)\nCalculated Molecular Weight: 115 kDa\nGenBank Accession Number: BC008786\nGene Symbol: Integrin alpha 5\nGene ID (NCBI): 3678\nRRID: AB_3672314\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: P08648\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2 - 8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888554922153,"sku":"98171-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-98171-1-rr","provider":"Iright","version":"1.0","type":"link"}