{"product_id":"proteintech-98189-1-rr","title":"Proteintech, 98189-1-RR, Anti-Human E-selectin\/CD62E Rabbit Recombinant Antibody","description":"Size: 100ug\nThe E-selectin\/CD62E (98189-1-RR) by Proteintech is a Recombinant antibody targeting E-selectin\/CD62E in FC applications with reactivity to human samples\n98189-1-RR targets E-selectin\/CD62E in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: TNF alpha treated HUVEC cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nE-selectin, also known as CD62E or ELAM-1, is a member of the selectin family of adhesion molecules that also includes L-selectin and P-selectin. E-selectin is an inducible endothelial cell surface molecule. Its expression on endothelial cells is transcriptionally upregulated by various proinflammatory substances such as IL-1, TNFα and lipopolysaccharide (LPS). Besides, it can be secreted by endothelial cells, and can be detected in a soluble form (sE-selectin) in serum. During inflammation, E-selectin plays an important part in recruiting leukocytes to the site of injury. (PMID: 2827173; 1382417; 8943958)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Recombinant Protein Predict reactive species\nFull Name: selectin E\nCalculated Molecular Weight: 610 aa, 67 kDa\nGenBank Accession Number: BC142711\nGene Symbol: CD62E\nGene ID (NCBI): 6401\nRRID: AB_3672328\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: P16581\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2 - 8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888549286057,"sku":"98189-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-98189-1-rr","provider":"Iright","version":"1.0","type":"link"}