{"product_id":"proteintech-98244-1-rr","title":"Proteintech, 98244-1-RR, Anti-Human FGFR2\/CD332 Rabbit Recombinant Antibody","description":"Size: 100ug\nThe FGFR2\/CD332 (98244-1-RR) by Proteintech is a Recombinant antibody targeting FGFR2\/CD332 in FC applications with reactivity to human samples\n98244-1-RR targets FGFR2\/CD332 in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: Transfected HEK-293T cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nFGFR2 (Fibroblast growth factor receptor 2), also known as CD332, is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration, and apoptosis. Ligand binding leads to the activation of several signaling pathways, such as RAS, MAPK1\/ERK2, MAPK3\/ERK1, and the MAP Kinase signaling pathway, as well as the AKT1 signaling pathway. Mutations in the gene of FGFR2 are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Recombinant protein Predict reactive species\nFull Name: fibroblast growth factor receptor 2\nCalculated Molecular Weight: 92kd\nGenBank Accession Number: NM_000141.4\nGene Symbol: FGFR2\nGene ID (NCBI): 2263\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: P21802\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2 - 8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888549548201,"sku":"98244-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-98244-1-rr","provider":"Iright","version":"1.0","type":"link"}