{"product_id":"proteintech-98296-2-rr","title":"Proteintech, 98296-2-RR, Anti-Human RANK\/TNFRSF11A Rabbit Recombinant Antibody","description":"Size: 100ug\nThe RANK\/TNFRSF11A (98296-2-RR) by Proteintech is a Recombinant antibody targeting RANK\/TNFRSF11A in FC applications with reactivity to human samples\n98296-2-RR targets RANK\/TNFRSF11A in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: Transfected CHO cells, K-562 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nTumor necrosis factor receptor superfamily member 11A (TNFRSF11A, also known as RANK, CD265, and ODFR) is the signaling receptor essential for osteoclast differentiation factor-mediated osteoclastogenesis and is involved in the regulation of interactions between T-cells and dendritic cells (PMID: 9878548). The RANK\/RANKL\/OPG system is a key regulator in bone resorption, and its dysregulation can lead to pathological bone loss (PMID: 37893470).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Eg3521 Product name: Recombinant Human RANK\/TNFRSF11A protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 30-212 aa of NM_003839 Sequence: IAPPCTSEKHYEHLGRCCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLP Predict reactive species\nFull Name: tumor necrosis factor receptor superfamily, member 11a, NFKB activator\nCalculated Molecular Weight: 66 kDa\nGenBank Accession Number: NM_003839\nGene Symbol: TNFRSF11A\nGene ID (NCBI): 8792\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q9Y6Q6\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2 - 8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888700805289,"sku":"98296-2-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-98296-2-rr","provider":"Iright","version":"1.0","type":"link"}