{"product_id":"proteintech-98531-5-rr","title":"Proteintech, 98531-5-RR, Anti-Human CD45RB\/RAB Rabbit Recombinant Antibody","description":"Size: 100ug\nThe CD45RB\/RAB (98531-5-RR) by Proteintech is a Recombinant antibody targeting CD45RB\/RAB in FC applications with reactivity to human samples\n98531-5-RR targets CD45RB\/RAB in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: FC receptor blocked human peripheral blood leukocyte, Transfected CHO-K1 Cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD45RB and CD45RAB are specific isoforms of CD45, a receptor-type protein tyrosine phosphatase (PTP) found on the surface of all nucleated hematopoietic cells, except mature erythrocytes and platelets. They serve as essential phenotypic markers to distinguish naïve T lymphocytes from antigen-experienced memory\/effector T cells. CD45RB and CD45RAB designations refer to specific isoforms of CD45 generated through alternative splicing of three variable exons (4, 5, and 6) in the PTPRC gene. These exons encode extracellular domains A, B, and C, respectively, which contain O-linked glycosylation sites that affect the molecule's size, charge, and ligand-binding properties. This antibody can detect CD45RB (contains exons B only) and CD45RAB (contains both exons A and B), but not CD45RABC (contain all three exons) or CD45RBC (contain exons B and C).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: protein tyrosine phosphatase, receptor type, C\nCalculated Molecular Weight: 147 kDa\nGenBank Accession Number: NM_002838.4\nGene Symbol: CD45\nGene ID (NCBI): 5788\nENSEMBL Gene ID: ENSG00000081237\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P08575-3\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2 - 8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888695955625,"sku":"98531-5-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-98531-5-rr","provider":"Iright","version":"1.0","type":"link"}