{"product_id":"proteintech-98576-2-rr","title":"Proteintech, 98576-2-RR, Anti-Mouse CD204 Rabbit Recombinant Antibody","description":"Size: 100ug\nThe CD204 (98576-2-RR) by Proteintech is a Recombinant antibody targeting CD204 in FC applications with reactivity to mouse samples\n98576-2-RR targets CD204 in FC applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: mouse peritoneal macrophages, RAW 264.7 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD204, also known as MSR1, belongs to the scavenger receptor family, which is mainly expressed on the surface of macrophages. CD204 plays a key inflammatory role in various pathophysiological processes, including atherosclerosis, innate and adaptive immunity, lung and liver disease, and cancer. CD204 binds to a variety of ligands, including modified low-density lipoproteins (LDL) and lipids, and is involved in endocytosis, positive regulation of cholesterol storage, and positive regulation of macrophage-derived foam cell differentiation. Studies have shown that CD204 is significantly increased in peripheral blood mononuclear cells (PBMCs) from patients with asthma and chronic obstructive pulmonary disease (COPD), which may serve as a disease marker.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Eg4727 Product name: Recombinant Mouse MSR1 protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-N-rFc Tag: N-rFc Domain: 79-458 aa of NM_001113326.1 Sequence: QLLNWEMKNCLVCSLNTSDTSQGPMEKENTSKVEMRFTIIMEHMKDMEERIESISNSKADLIDTERFQNFSMATDQRLNDILLQLNSLISSVQEHGNSLDAISKSLQSLNMTLLDVQLHTETLNVRVRESTAKQQEDISKLEERVYKVSAEVQSVKEEQAHVEQEVKQEVRVLNNITNDLRLKDWEHSQTLKNITFIQGPPGPQGEKGDRGLTGQTGPPGAPGIRGIPGVKGDRGQIGFPGGRGNPGAPGKPGRSGSPGPKGQKGEKGSVGGSTPLKTVRLVGGSGAHEGRVEIFHQGQWGTICDDRWDIRAGQVVCRSLGYQEVLAVHKRAHFGQGTGPIWLNEVMCFGRESSIENCKINQWGVLSCSHSEDAGVTCTS Predict reactive species\nFull Name: macrophage scavenger receptor 1\nCalculated Molecular Weight: 50 kDa\nGenBank Accession Number: NM_001113326.1\nGene Symbol: Msr1\nGene ID (NCBI): 20288\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P30204-1\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2 - 8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888565801129,"sku":"98576-2-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-98576-2-rr","provider":"Iright","version":"1.0","type":"link"}